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ORIGINAL ARTICLE
Year : 2019  |  Volume : 7  |  Issue : 4  |  Page : 120-126

A comparative study of concurrent infections of rickettsial infection, Malaria, Typhoid, and Chikungunya with Dengue


Department of Medicine, MVJ MC and RH, Bengaluru, Karnataka, India

Correspondence Address:
Dr. Vasantha Kamath
MVJ MC and RH, Dandupalya, National Highway 4, 30th Km Milestone, Kolathur P.O., Hoskote, Bengaluru - 562 114, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/AJIM.AJIM_3_19

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Introduction: In endemic countries such as India, the possibility that acute febrile illnesses are caused due to multiple infectious etiologies is not a rarity. In the postmonsoon season, dengue may often co-exist in the same patient concurrently with other infections such as scrub typhus, chikungunya, malaria, and typhoid. Materials and Methods: This is a prospective observational study aiming to understand the clinical and laboratory parameters and complications of concurrent infections such as typhoid, malaria, rickettsial infection, or chikungunya with dengue. Results: A total of 420 cases of dengue mono-infections were noted. Ninety-two of 512 patients with dengue were co-infected. The most common co-infection was dengue with rickettsiae (48.8%) followed by typhoid (22.2%). Rural, young, males were most affected by co-infections in contrast to mono-infections where rural and urban distribution is similar. The incidence of significant bleed increased in cases of malaria with dengue. Musculoskeletal, gastrointestinal, cardiac, and respiratory complications were seen in increased frequency in co-infections cases. Two deaths were noted in the co-infected groups of rickettsial diseases. Conclusion: The clinical picture and management of co-infected patients differ substantially from patients with mono-infections of dengue. Prompt recognition is necessary to allow the initiation of appropriate intervention in a timely manner. This excludes the possibility of increased morbidity and mortality, which is often avoidable.


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