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  Most cited articles *

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A comparative study of concurrent infections of rickettsial infection, Malaria, Typhoid, and Chikungunya with Dengue
Vasantha Kamath, Shreyashi Ganguly, BL Avinash
October-December 2019, 7(4):120-126
Introduction: In endemic countries such as India, the possibility that acute febrile illnesses are caused due to multiple infectious etiologies is not a rarity. In the postmonsoon season, dengue may often co-exist in the same patient concurrently with other infections such as scrub typhus, chikungunya, malaria, and typhoid. Materials and Methods: This is a prospective observational study aiming to understand the clinical and laboratory parameters and complications of concurrent infections such as typhoid, malaria, rickettsial infection, or chikungunya with dengue. Results: A total of 420 cases of dengue mono-infections were noted. Ninety-two of 512 patients with dengue were co-infected. The most common co-infection was dengue with rickettsiae (48.8%) followed by typhoid (22.2%). Rural, young, males were most affected by co-infections in contrast to mono-infections where rural and urban distribution is similar. The incidence of significant bleed increased in cases of malaria with dengue. Musculoskeletal, gastrointestinal, cardiac, and respiratory complications were seen in increased frequency in co-infections cases. Two deaths were noted in the co-infected groups of rickettsial diseases. Conclusion: The clinical picture and management of co-infected patients differ substantially from patients with mono-infections of dengue. Prompt recognition is necessary to allow the initiation of appropriate intervention in a timely manner. This excludes the possibility of increased morbidity and mortality, which is often avoidable.
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Medical education in India: Past, present, and future
Praveen Kulkarni, K Pushpalatha, Deepa Bhat
July-September 2019, 7(3):69-73
Medical education in global context has evolved over a period of time and so in India. With changing community needs, educational advancements and technological revolutions, we need to update the method of imparting knowledge and skills to the students. Major components of hidden curriculum like communication skills, attitude, empathy, altruism, professionalism, humanities etc need to be uncovered and delivered in a more systematic way. Ever increasing demand of doctors in the country has forced to establish new medical colleges across the country but the quality of Indian Medical Graduates produced out of them needs a lot to think and work upon. Reforms in curriculum Medical Council of India is planning to bring should be taken seriously and all efforts should be made to bring them to reality. In order to bring a competent Indian Medical Graduate in par with global standards should be the MANTRA of every medical education institution.
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Isolated Unilateral sixth Nerve palsy - Rare Case of post Dengue Encephalitis sequelae
Siddaganga , Sangram Biradar
April-June 2019, 7(2):33-36
Dengue fever is a common mosquito-borne viral infection endemic in tropical and subtropical countries. Neurological manifestations in dengue infection are relatively uncommon, and include encephalitis, encephalopathy, neuromuscular disorders and neuro-ocular disorders. Cranial mononeuropathy is a rare manifestation of dengue infection. A 20-year-old female was diagnosed with isolated, unilateral sixth cranial nerve palsy complicating dengue encephalitis. The patient was managed accordingly, and full ocular recovery was observed. This was the rare reported case of isolated sixth cranial nerve palsy associated with dengue fever encephalitis. It is important for clinicians to consider dengue as a differential diagnosis in patients presenting with fever and sixth cranial nerve palsy.
[ABSTRACT]   Full text not available  [PDF] [CITATIONS]
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Systemic lupus erythematosus and beta-thalassemia trait
M Narayana Swamy, TA Shilpa, Stephen Benny
January-March 2020, 8(1):22-23
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease that predominantly affects women of child-bearing age. The prevalence of beta-thalassemia in patients with SLE is lesser than the general population. When these two conditions coexist, however, SLE seems to have a more severe course. The following case report deals with a 34-year-old female who presented with severe dimorphic anemia and a positive direct Coombs test. On further evaluation, she was diagnosed with SLE based on a positive antineutrophilic antibody report and anti-Smith antibodies. A hemoglobin (Hb) electrophoresis was ordered for in view of the normal iron profile which revealed beta-thalassemia trait. An improvement in Hb and platelet counts was noted after initiating steroids. Although most hematological abnormalities are due to the disease (SLE) itself, it is important to remember that other causes such as thalassemia may coexist.
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Anticalcitonin gene-related peptide monoclonal antibodies: An overview
Jamir Pitton Rissardo, Ana Letícia Fornari Caprara
January-March 2020, 8(1):33-34
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Training undergraduate medical students on research methodology in the competency-based curriculum
Saurabh RamBihariLal Shrivastava, Prateek Saurabh Shrivastava
January-March 2020, 8(1):35-36
  1 791 87
Coronavirus disease 2019 and the kidney
Ravi Jangamani, Chakravarthy Thirumal, Sankaran Sundar
October-December 2020, 8(4):172-178
Coronavirus disease 2019 (COVID-19) is a highly contagious infection caused by severe acute respiratory syndrome coronavirus-2, primarily manifesting as acute respiratory illness but can affect multiple organs. The COVID-19 individuals have varied renal manifestations which includes acute kidney injury, proteinuria, and hematuria. The involvement of kidneys indicates the severity of illness and is one of the determinants of mortality. The individuals with chronic kidney diseases (CKD), on dialysis and with kidney transplantation are at higher risk of severe COVID-19 infection due to the poor immune response and a high prevalence of comorbidities. Here, we review the effects of COVID-19 on kidneys and its management in CKD, dialysis, and kidney transplantation individuals.
  1 1,786 133
Patient based factors influencing drug compliance in a tertiary care hospital in Mysore..A pilot study
H Basavanagowadappa, Kavita Yadav, BM Srinivasa, HS Kavitha
October-December 2017, 5(4):17-21
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